We are thrilled to announce that the groundbreaking research conducted by Dr. Pei Leisi and her collaborators has been published in Proceedings of the National Academy of Sciences (PNAS), one of the world’s most prestigious multidisciplinary scientific journals.
Key Discoveries and Scientific Impact
Inspired by the intense engagement of video game players, this research hypothesized that distinct brain activity patterns occur during gaming compared to a generic nongame setting. Through large-scale EEG experiments, they identified a unique brain response pattern, termed P300-CE, during gameplay, characterized by unusually large magnitudes and a lack of adaptation over repeated exposure. The identification of this distinctive response component in gaming contexts may inspire further research into fundamental cognitive systems, such as motivation, reward, emotional engagement, and their dynamic interplay in gaming environments and highlight the value of gaming contexts for studying sustained neural excitation and opens broad avenues for neural cognitive research.
The Prestige of PNAS
PNAS is universally regarded as one of the most prestigious and impactful multidisciplinary scientific journals. Its unique association with the US National Academy of Sciences, broad scope spanning biology, physical sciences, and social sciences, and rigorous peer-review standards cement its position as a cornerstone of top-tier scientific communication. With a high impact factor and a storied history of publishing transformative research, PNAS stands as a leader in advancing scientific discovery and continues to shape the landscape of cutting-edge science.
Reference
Pei, L., Green, C. S., & Ouyang, G. (2025). Characterizing a highly excited and sustained brain response activity during gaming: P300-CE. Proceedings of the National Academy of Sciences, 122(30), e2502135122. doi:10.1073/pnas.2502135122
You are welcome to read the paper online for more details!