°ò¦]­«²Õ§Þ³N (Recombinant DNA Technology)

Stanley Cohen ©M Herbert Boyer ©ó1973¦~µo©ú¤F°ò¦]­«²Õ§Þ³N¡C ³o§Þ³N¬O±N°ò¦]±q¤@¥Íª«ÅéÂಾ¨ì¥t¤@¥Íª«Å餺ªº¡C

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°ò¦]½Æ»s (Gene Cloning)

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³æ§J¶©§ÜÅé (Monoclonal Antibodies Production)

1975¦~ Kohler ©M Milstein »s³y¤FÂøºØ½F²Ó­M®è(Hybridoma cells)¡C

±N¤p¹«ªºB²Ó­M (B Cell) »P½F²Ó­M (Cancer cell)¿Ä¦X¡A»s¦¨¥i¦bÅé¥~³sÄò°ö¾i¨Ã¯à¤Àªc§ÜÅé (Antibody) ªºÂøºØ½F²Ó­M®è¡C

¸Ó²Ó­M®è©Ò¤Àªcªº§ÜÅé³£§t¦³¬Û¦Pªº§ÜÅé¤À¤l¸s¡A¥¦­Ì³£¹ï³æ¤@ºØ§Ü­ì (Antigen) ªí²{±M¤@©Ê¡C

¥Ñ©ó¦¹§ÜÅé¬O¥ÑB²Ó­M³æ§J¶©²£¥Í¡A¬G¦W¬°³æ§J¶©§ÜÅé (Monoclonal antibody)¡C

¦h»EžJÃ즡¤ÏÀ³ (Polymerase Chain Reaction - PCR)

1985¦~¡AK.B. Mullis ©M¥Lªº¦Pµ¡­Ìµo©ú¤F¥Î¦h»EžJÃ즡¤ÏÀ³ (PCR) ¤èªk¥h¶i¦æÅé¥~ÂX¼W°ò¦]¡A±N¿ï©wªº°ò¦]¤ù¬q©ñ¤j½Æ»s¹L¦Ê¸U­¿¡C

PCRªºÀ³¥Î¬Æ¼s¡A¥¦¥i¥HºÊ©w²Óµßªº¦s¦b¡A¤j¶q½Æ»s¥Í²£©Ò»ÝªºDNA¡A¤Î¶EÂ_¿ò¶Ç¯fµ¥¡C


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